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021-54845833/15800441009
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Background: |
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
TNFSF12 |
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Immunogen: |
Synthesized peptide derived from internal of human TNF12. |
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Full name: |
tumor necrosis factor (ligand) superfamily, member 12 |
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Synonyms： |
APO3L; DR3LG; TWEAK |
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SwissProt: |
O43508 |
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IHC positive control: |
Human brain tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
27 kDa |
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WB Positive control: |
COLO cells, Huvec cells and 293 cells lysates |
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WB Recommended dilution: |
500-3000 |
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IF positive control: |
Hela cells |
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IF Recommend dilution: |
100-500 |
