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Background: |
This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. Multiple alternatively spliced transcript variants that encode different proteins have been described. |
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Applications: |
WB |
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Name of antibody: |
TCF4/12 |
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Immunogen: |
Synthesized peptide derived from internal of human TCF4/12. |
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Full name: |
transcription factor 4/12 |
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Synonyms： |
E2-2; ITF2; PTHS; SEF2; ITF-2; SEF-2; TCF-4; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; bHLHb19/HEB; CRS3; HTF4; bHLHb20; HsT17266 |
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SwissProt: |
P15884/Q99081 |
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WB Predicted band size: |
71 kDa |
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WB Positive control: |
Huvec cells lysate |
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WB Recommended dilution: |
500-3000 |
