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021-54845833/15800441009
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Background: |
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]). |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SULF2 |
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Immunogen: |
Synthetic peptide of human SULF2 |
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Full name: |
sulfatase 2 |
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Synonyms: |
HSULF-2 |
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SwissProt: |
Q8IWU5 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil |
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IHC Recommend dilution: |
20-100 |
