购物车
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021-54845833/15800441009
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Background: |
This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants. |
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Applications: |
ELISA, WB |
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Name of antibody: |
GPT2 |
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Immunogen: |
Synthetic peptide of human GPT2 |
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Full name: |
glutamic--pyruvic transaminase 2 |
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Synonyms: |
ALT2; GPT 2; MRT49 |
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SwissProt: |
Q8TD30 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
58 kDa |
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WB Positive control: |
Human fetal brain tissue lysate |
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WB Recommended dilution: |
200-1000 |
