ÖÐÎÄÃû³Æ£º Íÿ¹PRMT2¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-PRMT2 rabbit polyclonal antibody
±ð Ãû£º HRMT1L1
¿¹ Ô£º PRMT2
´¢ ´æ£º Àä¶³£¨-20¡æ£©
ËÞ Ö÷£º Rabbit
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·´Ó¦ÖÖÊô£º Human
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
Protein arginine N-methyltransferase 2 is an enzyme that in humans is encoded by the PRMT2 gene. Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
PRMT2 |
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Immunogen: |
Fusion protein of human PRMT2 |
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Full name: |
protein arginine methyltransferase 2 |
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Synonyms£º |
HRMT1L1 |
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SwissProt: |
P55345 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human tonsil and human ovarian cancer |
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IHC Recommend dilution: |
25-100 |

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021-54845833/15800441009
