ÖÐÎÄÃû³Æ£º Íÿ¹PRKCQ (Phospho-Ser695)¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-PRKCQ (Phospho-Ser695) rabbit polyclonal antibody
±ð Ãû£º PRKCT; nPKC-theta
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º PRKCQ (Phospho-Ser695)
·´Ó¦ÖÖÊô£º Human
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. |
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Applications: |
WB, IHC |
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Name of antibody: |
PRKCQ (Phospho-Ser695) |
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Immunogen: |
Synthetic peptide of human PRKCQ (Phospho-Ser695) |
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Full name: |
protein kinase C, theta (Phospho-Ser695) |
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Synonyms£º |
PRKCT; nPKC-theta |
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SwissProt: |
Q04759 |
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IHC positive control: |
Human lung carcinoma |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
82 kDa |
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WB Positive control: |
293 cells treated with PMA |
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WB Recommended dilution: |
500-1000 |


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021-54845833/15800441009
