购物车
帮助
021-54845833/15800441009
中文名称： 兔抗POLR3H多克隆抗体
英文名称： Anti-POLR3H rabbit polyclonal antibody
别 名： RPC8; RPC22.9
抗 原： POLR3H
储 存： 冷冻（-20℃） 避光
宿 主： Rabbit
反应种属： Human Mouse Rat
相关类别： 一抗
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
|
Background: |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway By similarity. |
|
Applications: |
WB |
|
Name of antibody: |
POLR3H |
|
Immunogen: |
Synthesized peptide derived from internal of human RPC8. |
|
Full name: |
polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) |
|
Synonyms： |
RPC8; RPC22.9 |
|
SwissProt: |
Q9Y535 |
|
WB Predicted band size: |
23 kDa |
|
WB Positive control: |
K562 cells lysate |
|
WB Recommended dilution: |
500-3000 |
