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ÖÐÎÄÃû³Æ£º  Íÿ¹PFKFB2¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ£º  Anti-PFKFB2 rabbit polyclonal antibody


±ð       Ãû£º  PFK-2/FBPase-2


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¿¹       Ô­£º  PFKFB2


ËÞ       Ö÷£º  Rabbit


·´Ó¦ÖÖÊô£º  Human, Mouse


±ê  ¼Ç  Î Unconjugate


¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.

Applications:

ELISA, WB

Name of antibody:

PFKFB2

Immunogen:

Synthetic peptide of human PFKFB2

Full name:

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

Synonyms£º

PFK-2/FBPase-2

SwissProt:

O60825

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

58 kDa

WB Positive control:

NIH/3T3 cells

WB Recommended dilution:

200-1000




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