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    ÖÐÎÄÃû³Æ£º Íÿ¹PEG3¶à¿Ë¡¿¹Ìå


    Ó¢ÎÄÃû³Æ£º Anti-PEG3 rabbit polyclonal antibody


    ±ð       Ãû£º PW1; ZNF904; ZSCAN24; ZKSCAN22


    ¿¹      Ô­£º PEG3


    Ïà¹ØÀà±ð£º Ò»¿¹


    ´¢      ´æ£º Àä¶³£¨-20¡æ£©


    ËÞ      Ö÷£º Rabbit


    ·´Ó¦ÖÖÊô£º Human


    ±ê  ¼Ç  Î Unconjugate


    ¿Ë¡ÀàÐÍ£º rabbit polyclonal


    ¼¼Êõ¹æ¸ñ

    Background:

    In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.

    Applications:

    ELISA, IHC

    Name of antibody:

    PEG3

    Immunogen:

    Synthetic peptide of human PEG3

    Full name:

    paternally expressed 3

    Synonyms£º

    PW1; ZNF904; ZSCAN24; ZKSCAN22

    SwissProt:

    Q9GZU2

    ELISA Recommended dilution:

    5000-10000

    IHC positive control:

    Human colorectal cancer and Human tonsil

    IHC Recommend dilution:

    25-100







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