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    • Íÿ¹RRM2B¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ£º  Íÿ¹RRM2B¶à¿Ë¡¿¹Ìå  

    Ó¢ÎÄÃû³Æ£º Anti-RRM2B rabbit polyclonal antibody

    ±ð    Ãû£º P53R2; MTDPS8A; MTDPS8B

    Ïà¹ØÀà±ð£º Ò»¿¹

    ´¢    ´æ£º Àä¶³£¨-20¡æ£© ±Ü¹â

    ËÞ    Ö÷£º Rabbit

    ¿¹    Ô­£º RRM2B

    ·´Ó¦ÖÖÊô£º Human Mouse Rat

    ±ê ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º Unconjugate

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    Background:

    This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.

    Applications:

    WB

    Name of antibody:

    RRM2B

    Immunogen:

    Synthesized peptide derived from Internal of human RRM2B.

    Full name:

    ribonucleotide reductase M2 B (TP53 inducible)

    Synonyms£º

    P53R2; MTDPS8A; MTDPS8B

    SwissProt:

    Q7LG56

    WB Predicted band size:

    41 kDa

    WB Positive control:

    COLO205 cells lysate

    WB Recommended dilution:

    500-3000



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