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ÖÐÎÄÃû³Æ£º Íÿ¹NCOR2¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ£º Anti-NCOR2 rabbit polyclonal antibody


±ð       Ãû£º SMRT; TRAC; CTG26; SMRTE; TRAC1; N-CoR2; TNRC14; TRAC-1; SMAP270; SMRTE-tau


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ËÞ       Ö÷£º Rabbit


¿¹       Ô­£º NCOR2


·´Ó¦ÖÖÊô£º Human


±ê  ¼Ç  Î Unconjugate


¿Ë¡ÀàÐÍ£º rabbit polyclonal


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Background:

This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.

Applications:

ELISA, IHC

Name of antibody:

NCOR2

Immunogen:

Synthetic peptide of human NCOR2

Full name:

nuclear receptor corepressor 2

Synonyms£º

SMRT; TRAC; CTG26; SMRTE; TRAC1; N-CoR2; TNRC14; TRAC-1; SMAP270; SMRTE-tau

SwissProt:

Q9Y618

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human cervical cancer

IHC Recommend dilution:

25-100




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