ÖÐÎÄÃû³Æ£º Íÿ¹MYSM1¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-MYSM1 rabbit polyclonal antibody
±ð Ãû£º 2ADUB, 2A-DUB, RP4-592A1.1
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º MYSM1
·´Ó¦ÖÖÊô£º Human
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5. Binds histones |
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Applications: |
ELISA, IHC |
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Name of antibody: |
MYSM1 |
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Immunogen: |
Synthetic peptide of human MYSM1 |
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Full name: |
Myb-like, SWIRM and MPN domains 1 |
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Synonyms£º |
2ADUB, 2A-DUB, RP4-592A1.1 |
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SwissProt: |
Q5VVJ2 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human ovarian cancer |
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IHC Recommend dilution: |
50-200 |


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