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ÖÐÎÄÃû³Æ£º   Íÿ¹MYSM1¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ£º  Anti-MYSM1 rabbit polyclonal antibody


±ð       Ãû£º  2ADUB, 2A-DUB, RP4-592A1.1


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ËÞ      Ö÷£º  Rabbit


¿¹      Ô­£º  MYSM1


·´Ó¦ÖÖÊô£º  Human


±ê  ¼Ç  Î  Unconjugate


¿Ë¡ÀàÐÍ£º  rabbit polyclonal


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Background:

Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5. Binds histones

Applications:

ELISA, IHC

Name of antibody:

MYSM1

Immunogen:

Synthetic peptide of human MYSM1

Full name:

Myb-like, SWIRM and MPN domains 1

Synonyms£º

2ADUB, 2A-DUB, RP4-592A1.1

SwissProt:

Q5VVJ2

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human ovarian cancer

IHC Recommend dilution:

50-200





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