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021-54845833/15800441009
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Background: |
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
FGFR2 |
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Immunogen: |
Synthetic peptide of human FGFR2 |
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Full name: |
Fibroblast growth factor receptor 2 |
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Synonyms： |
BEK, JWS, BBDS, CEK3, CFD1, ECT1, KGFR, TK14, TK25, BFR-1, CD332, K-SAM |
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SwissProt: |
P21802 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human thyroid cancer and Human brain |
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IHC Recommend dilution: |
25-100 |
