购物车
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021-54845833/15800441009
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Background: |
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
FBH1 |
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Immunogen: |
Fusion protein of human FBH1 |
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Full name: |
F-box DNA helicase 1 |
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Synonyms: |
Fbx18; hFBH1; FBXO18 |
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SwissProt: |
Q8NFZ0 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human gastric cancer |
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IHC Recommend dilution: |
100-300 |
