ÖÐÎÄÃû³Æ£º Íÿ¹MRPL22¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-MRPL22 rabbit polyclonal antibody
±ð Ãû£º mitochondrial ribosomal protein L22; L22mt; RPML25; HSPC158; MRP-L22; MRP-L25
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º MRPL22
·´Ó¦ÖÖÊô£º Human, Mouse, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
MRPL22 |
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Immunogen: |
Fusion protein of human MRPL22 |
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Full name: |
mitochondrial ribosomal protein L22 |
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Synonyms: |
L22mt; RPML25; HSPC158; MRP-L22; MRP-L25 |
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SwissProt: |
Q9NWU5 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
50-200 |
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021-54845833/15800441009
