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    ÖÐÎÄÃû³Æ£º ZWINT¿¹Ô­£¨ÖØ×éµ°°×£©

    Ó¢ÎÄÃû³Æ£º ZWINT Antigen (Recombinant Protein)

    ±ð    Ãû£º   ZWINT1; KNTC2AP; HZwint-1

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    Full length fusion protein

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    Full name:

    ZW10 interacting kinetochore protein

    Synonyms:

    ZWINT1; KNTC2AP; HZwint-1

    Swissprot:

    O95229

    Gene Accession:

    BC020979

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.



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