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    ÖÐÎÄÃû³Æ£º  KARS1 ¿¹Ô­£¨ÖØ×éµ°°×£©

    Ó¢ÎÄÃû³Æ£º KARS1 Antigen (Recombinant Protein)

    ±ð      Ãû£º lysyl-tRNA synthetase 1; KRS; KARS; KARS2; CMTRIB; DFNB89

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    Fusion protein corresponding to a region derived from 348-597 amino acids of human KARS1


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    Full name:

    lysyl-tRNA synthetase 1

    Synonyms:

    KRS; KARS; KARS2; CMTRIB; DFNB89

    Swissprot:

    Q15046

    Gene Accession:

    BC004132

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]


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