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中文名称：TGM2 抗原（重组蛋白）
英文名称： TGM2 Antigen (Recombinant Protein)
别 名： Transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase); TG2; TGC; GNAH; G-ALPHA-h
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to C terminal 250 amino acids of human TGM2 |
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Full name: |
Transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) |
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Synonyms: |
TG2; TGC; GNAH; G-ALPHA-h |
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Swissprot: |
P21980 |
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Gene Accession: |
BC003551 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. |
