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Ó¢ÎÄÃû³Æ£º RBM5 Antigen (Recombinant Protein)

±ð      Ãû£º RNA binding motif protein 5; G15; H37; RMB5; LUCA15

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Fusion protein corresponding to N terminal 250 amino acids of human RBM5


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Full name:

RNA binding motif protein 5

Synonyms:

G15; H37; RMB5; LUCA15

Swissprot:

P52756

Gene Accession:

BC002957

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.




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