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中文名称：SIGMAR1抗原（重组蛋白）
英文名称： SIGMAR1 Antigen (Recombinant Protein)
别 名： SRBP; ALS16; OPRS1; SR-BP; SIG-1R; SR-BP1; sigma1R
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from 102-223 amino acids of human SIGMAR1 |
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Full name: |
sigma non-opioid intracellular receptor 1 |
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Synonyms: |
SRBP; ALS16; OPRS1; SR-BP; SIG-1R; SR-BP1; sigma1R |
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Swissprot: |
Q99720 |
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Gene Accession: |
BC004899 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. |
