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中文名称：ALDH3A1 抗原（重组蛋白）
英文名称： ALDH3A1 Antigen (Recombinant Protein)
别 名： aldehyde dehydrogenase 3 family, member A1; ALDH3; ALDHIII
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to C terminal 300 amino acids of human ALDH3A1 |
|
Full name: |
aldehyde dehydrogenase 3 family, member A1 |
|
Synonyms: |
ALDH3; ALDHIII |
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Swissprot: |
P30838 |
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Gene Accession: |
BC004370 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
