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ÖÐÎÄÃû³Æ£º Íÿ¹ADSL¶à¿Ë¡¿¹Ìå

Ó¢ÎÄÃû³Æ£º Anti-ADSL rabbit polyclonal antibody

±ð      Ãû£º ASL; AMPS; ASASE

Ïà¹ØÀà±ð£º Ò»¿¹

´¢      ´æ£º Àä¶³£¨-20¡æ£©

¿¹      Ô­£º ADSL

ËÞ      Ö÷£º Rabbit

·´Ó¦ÖÖÊô£º Human, Mouse

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

ADSL

Immunogen:

Fusion protein of human ADSL

Full name:

adenylosuccinate lyase

Synonyms£º

ASL; AMPS; ASASE

SwissProt:

P30566

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human breast cancer and Human lung cancer

IHC Recommend dilution:

15-50




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