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Fusion protein corresponding to a region derived from 1-183 amino acids of human FTH1 |
技术规格
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Full name: |
Ferritin, heavy polypeptide 1 |
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Synonyms: |
FHC, FTH, PLIF, FTHL6, PIG15 |
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Swissprot: |
P02794 |
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Gene Accession: |
BC000857 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. |
