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帮助
021-54845833/15800441009
技术规格
Background:
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
Applications:
ELISA, WB, IHC
Name of antibody:
KRT81
Immunogen:
Fusion protein of human KRT81
Full name:
keratin 81
Synonyms:
HB1; Hb-1; KRTHB1; MLN137; ghHkb1; hHAKB2-1
SwissProt:
Q14533
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human colorectal cancer and Human thyroid cancer
IHC Recommend dilution:
50-200
WB Predicted band size:
55 kDa
WB Positive control:
Hela cell lysate
WB Recommended dilution:
200-1000
