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Background: |
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
KLRC1 |
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Immunogen: |
Fusion protein of human KLRC1 |
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Full name: |
killer cell lectin-like receptor subfamily C, member 1 |
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Synonyms: |
NKG2; NKG2A; CD159A |
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SwissProt: |
P26715 |
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IHC positive control: |
Human gastric cancer and human thyroid cancer |
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IHC Recommend dilution: |
50-200 |
